{"id":1200,"date":"2024-01-17T14:02:21","date_gmt":"2024-01-17T14:02:21","guid":{"rendered":"https:\/\/www.the-nash-education-program.com\/?page_id=1200"},"modified":"2024-01-17T14:02:21","modified_gmt":"2024-01-17T14:02:21","slug":"como-se-diagnostica-nash","status":"publish","type":"page","link":"https:\/\/www.the-nash-education-program.com\/es\/que-es-nash\/como-se-diagnostica-nash\/","title":{"rendered":"\u00bfC\u00d3MO SE DIAGNOSTICA NASH?"},"content":{"rendered":"\n<p><strong>Como enfermedad silenciosa y progresiva, NASH a menudo puede permanecer sin detectarse hasta que ya ha avanzado a etapas m\u00e1s graves y potencialmente mortales. La detecci\u00f3n temprana es uno de los desaf\u00edos m\u00e1s grandes relacionados con el diagn\u00f3stico y control de NASH.<sup>1-3<\/sup>&nbsp;Pero la concientizaci\u00f3n y la educaci\u00f3n pueden ayudar a cambiar eso.<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/www.waybackmachinedownloader.com\/scraping\/files\/live\/the-nash-education-program.com_georgenjenga69_yahoo.com_zyrp7w0mtc\/wp-content\/uploads\/2018\/03\/syringe.png\" alt=\"\"\/><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\">PRUEBA POR EXCELENCIA ACTUAL: BIOPSIA DE H\u00cdGADO<\/h4>\n\n\n\n<p>En la actualidad, el diagn\u00f3stico de NASH con frecuencia se establece formalmente mediante una biopsia de h\u00edgado. Pero este procedimiento invasivo, si bien actualmente es la prueba por excelencia, puede ser costoso, inc\u00f3modo y potencialmente riesgoso para los pacientes.<sup>4<\/sup>&nbsp;Adem\u00e1s, es muy limitada la cantidad de especialistas disponibles para realizar e interpretar una biopsia, comparada con la cantidad de pacientes que se presume que tienen NASH, lo cual hace que sea poco pr\u00e1ctico como parte de la rutina cl\u00ednica habitual.<sup>3<\/sup>&nbsp;As\u00ed, la biopsia de h\u00edgado representa una restricci\u00f3n significativa para que una mayor poblaci\u00f3n acceda al diagn\u00f3stico.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/www.waybackmachinedownloader.com\/scraping\/files\/live\/the-nash-education-program.com_georgenjenga69_yahoo.com_zyrp7w0mtc\/wp-content\/uploads\/2018\/03\/ultrasound.png\" alt=\"\"\/><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\">OTROS M\u00c9TODOS DIAGN\u00d3STICOS<\/h4>\n\n\n\n<p>Entre los m\u00e9todos diagn\u00f3sticos no invasivos alternativos se incluyen las t\u00e9cnicas basadas en im\u00e1genes:<sup>4-6<\/sup><\/p>\n\n\n\n<ul>\n<li>Ultrasonido (NAFLD).<\/li>\n\n\n\n<li>Resonancia magn\u00e9tica (MRI) (NAFLD).<\/li>\n\n\n\n<li>Elastograf\u00eda transitoria (NAFLD, Fibrosis).<\/li>\n\n\n\n<li>Elastograf\u00eda por ultrasonido (Fibrosis).<\/li>\n\n\n\n<li>Elastograf\u00eda por resonancia magn\u00e9tica (MRE) (Fibrosis).<\/li>\n<\/ul>\n\n\n\n<p>Lamentablemente, ninguno de estos m\u00e9todos se dise\u00f1\u00f3 originalmente para diagnosticar todas las caracter\u00edsticas de NASH. Si bien estas t\u00e9cnicas pueden ser eficaces, algunas son demasiado costosas y llevan mucho tiempo. Adem\u00e1s, todas exigen el uso y la interpretaci\u00f3n de expertos que impiden el acceso generalizado en la atenci\u00f3n primaria, lo cual a su vez demora o complica el proceso de diagnosticar NASH.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/www.waybackmachinedownloader.com\/scraping\/files\/live\/the-nash-education-program.com_georgenjenga69_yahoo.com_zyrp7w0mtc\/wp-content\/uploads\/2018\/03\/blood.png\" alt=\"\"\/><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\">AN\u00c1LISIS DE SANGRE<\/h4>\n\n\n\n<p>Durante a\u00f1os, los especialistas han intentado cuantificar el riesgo de una enfermedad hep\u00e1tica en los pacientes mediante el an\u00e1lisis de sangre de rutina (p.&nbsp;ej., niveles de enzimas hep\u00e1ticas [aspartato aminotransferasa (AST), alanina transaminasa (ALT)], plaquetas). Sin embargo, estos biomarcadores generales no son suficientes por s\u00ed solos como herramientas diagn\u00f3sticas confiables para NASH y la fibrosis, ya que, com\u00fanmente, los niveles de ALT o AST pueden ser normales en los pacientes con NAFLD e incluso NASH.<sup>5<\/sup><\/p>\n\n\n\n<p>Se necesitan con urgencia t\u00e9cnicas diagn\u00f3sticas no invasivas, ya sean biomarcadores en sangre o biomarcadores de imagen, para permitir el acceso al diagn\u00f3stico exacto de NASH a la mayor\u00eda de la poblaci\u00f3n generalizada que lo necesita.<sup>7<\/sup><\/p>\n\n\n\n<p>Si se validan como reemplazo de la biopsia de h\u00edgado, dichos biomarcadores podr\u00edan acelerar significativamente el desarrollo de f\u00e1rmacos en NAFLD. La FDA alienta a los patrocinadores para que consideren el desarrollo de biomarcadores.<sup>7<\/sup><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">EL FUTURO DEL DIAGN\u00d3STICO DE NASH<\/h4>\n\n\n\n<p>Afortunadamente, se est\u00e1n desarrollando nuevas t\u00e9cnicas diagn\u00f3sticas de bajo costo y no invasivas para NASH que est\u00e1n demostrando una mejor precisi\u00f3n. Se espera que en los pr\u00f3ximos a\u00f1os brinden un acceso mucho m\u00e1s amplio al diagn\u00f3stico exacto de NASH.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">C\u00d3MO HACER EL DIAGN\u00d3STICO<\/h4>\n\n\n\n<p>La manera en que diagnosticamos NASH est\u00e1 cambiando. Pero no siempre es sencillo. Descargue las pautas de referencia actuales sobre NASH:<\/p>\n\n\n\n<ul>\n<li><a href=\"https:\/\/www.the-nash-education-program.com\/wp-content\/uploads\/2018\/01\/NAFLD-Guidance-2018.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">\u201cThe Diagnosis and Management of Nonalcoholic Fatty Liver Disease: Practice Guidance From the American Association for the Study of Liver Diseases\u201d [Diagn\u00f3stico y control de NAFLD: Gu\u00eda Pr\u00e1ctica de la Asociaci\u00f3n Estadounidense para el Estudio de Enfermedades Hep\u00e1ticas]<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.the-nash-education-program.com\/wp-content\/uploads\/2018\/01\/English-report.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">\u201cEASL\u2013EASD\u2013EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease\u201d [Pautas de la Pr\u00e1ctica Cl\u00ednica para el control de NAFLD]<\/a><\/li>\n<\/ul>\n\n\n\n<p><a href=\"https:\/\/www.waybackmachinedownloader.com\/scraping\/files\/live\/the-nash-education-program.com_georgenjenga69_yahoo.com_zyrp7w0mtc\/es\/que-es-nash\/cuales-son-las-consecuencias-de-nash\/\"><\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.waybackmachinedownloader.com\/scraping\/files\/live\/the-nash-education-program.com_georgenjenga69_yahoo.com_zyrp7w0mtc\/es\/que-es-nash\/cuales-son-las-consecuencias-de-nash\/\">\u00bfCU\u00c1LES SON LAS CONSECUENCIAS DE NASH?<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.waybackmachinedownloader.com\/scraping\/files\/live\/the-nash-education-program.com_georgenjenga69_yahoo.com_zyrp7w0mtc\/es\/folletos-educativos\/\">EXPLORE NUESTROS FOLLETOS EDUCATIVOS<\/a><\/p>\n\n\n\n<p>Referencias<\/p>\n\n\n\n<ol>\n<li>Mayo Clinic. Nonalcoholic fatty liver disease. https:\/\/www.mayoclinic.org\/diseases-conditions\/nonalcoholic-fatty-liver-disease\/symptoms-causes\/syc-20354567?p=1. Accessed October 7, 2019.<\/li>\n\n\n\n<li>Polis S, Fernandez R. Impact of physical and psychological factors on health-related quality of life in adult patients with liver cirrhosis: a systematic review protocol. JBI Database System Rev Implement Rep. 2015;13(1)39-51.<\/li>\n\n\n\n<li>Younossi, ZM, Koenig AB, Abdelatif D, et al. Global epidemiology of nonalcoholic fatty liver disease -Meta-analytic assessment of prevalence, incidence, and outcomes.&nbsp;<em>Hepatology<\/em>. 2016;64(1):73-84.<\/li>\n\n\n\n<li>Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of non- alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association.&nbsp;<em>Hepatology<\/em>. 2012;55(6):2005-2023.<\/li>\n\n\n\n<li>European Association for the Study of the Liver (EASL); European Association for the Study of Diabetes (EASD); European Association for the Study of Obesity (EASO). EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease.&nbsp;<em>J Hepatol<\/em>, 2016;64(6):1388-1402.<\/li>\n\n\n\n<li>Rinella ME, Sanyal AJ. Management of NAFLD: a stage-based approach.&nbsp;<em>Nature<\/em>. 2016;13:196-205.<\/li>\n\n\n\n<li>Center for Drug Evaluation and Research (CDER). Noncirrhotic nonalcoholic steatohepatitis with liver fibrosis: developing drugs for treatment, guidance for industry, draft guidance. https:\/\/www.fda.gov\/media\/119044\/download. Published December 2018. Accessed October 11, 2019.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Como enfermedad silenciosa y progresiva, NASH a menudo puede permanecer sin detectarse hasta que ya ha avanzado a etapas m\u00e1s &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"\u00bfC\u00d3MO SE DIAGNOSTICA NASH?\" class=\"read-more button\" href=\"https:\/\/www.the-nash-education-program.com\/es\/que-es-nash\/como-se-diagnostica-nash\/#more-1200\" aria-label=\"More on \u00bfC\u00d3MO SE DIAGNOSTICA NASH?\">Read more<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":1189,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ub_ctt_via":"","footnotes":""},"featured_image_src":null,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.9.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u00bfC\u00d3MO SE DIAGNOSTICA NASH? - NASH Disease<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.the-nash-education-program.com\/es\/que-es-nash\/como-se-diagnostica-nash\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u00bfC\u00d3MO SE DIAGNOSTICA NASH? - NASH Disease\" \/>\n<meta property=\"og:description\" content=\"Como enfermedad silenciosa y progresiva, NASH a menudo puede permanecer sin detectarse hasta que ya ha avanzado a etapas m\u00e1s ... 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